Wednesday, June 20, 2007

Heart survival 'higher in obese'

Heart survival 'higher in obese'
Obese heart attack and angina patients are more likely to survive after treatment, a study suggests.

Researchers found obese patients were less than half as likely to die in the three years after treatment as patients with a normal body mass index.

The German and Swiss study - involving 1,676 patients and in the European Heart Journal - could not explain why.

And experts warned obese people were more likely to develop heart problems in the first place.

The evidence from our study shows once a coronary event has occurred and been optimally treated, obese patients switch to a more favourable prognosis
Dr Heinz Buettner

The study followed 1,676 patients who were hospitalised with unstable angina or a specific type of heart attack called a non-ST-segment elevation myocardial infarction.

Standard treatment was a coronary angiography to diagnose the extent of the problem, followed by a process to unblock the arteries called coronary revascularisation or a coronary artery bypass graft.

Lead researcher Dr Heinz Buettner said: "Although there is no doubt that people who are overweight, obese and very obese have a higher risk of developing diabetes, hypertension and coronary artery disease, the evidence from our study shows once a coronary event has occurred and been optimally treated, obese patients switch to a more favourable prognosis compared to normal weight patients."

The obese patients tended to be younger than the normal weight patients, and were more likely to be given prescriptions for heart drugs such as statins and beta-blockers on discharge from hospital.

But Dr Buettner said his analysis suggested that neither of these two factors could fully explain the lower mortality rate.

Protective effect

He said it was possible that differences in body chemistry caused by obesity might play a role.

For instance, levels of blood platelets, which can affect clotting, are lower in obese patients, while levels of fat in the heart tissue, which might have a protective effect, are higher.

Another theory is that the higher levels of endogenous cannabinoids in obese people might be key. There is a growing body of evidence to suggest that these chemicals have a protective effect during a heart attack.

Dr Buettner said it was important that obese people made efforts to lose weight.

He said: "Not all patients can be treated with early revascularisation because an acute coronary syndrome always has the risk of sudden cardiac death.

"It is well known that even a modest intentional weight loss can improve or prevent obesity-related cardiovascular risk factors."

June Davison, of the British Heart Foundation, said the study raised more questions than it answered.

"Further research is needed for us to understand the reasons for this link," she said.

"What we are sure of, is that if you are overweight you have a higher risk of developing high blood pressure, coronary heart disease and diabetes in the first place."

Story from BBC NEWS:

Tuesday, June 19, 2007

Estrogen-Depression Connection?


I would greatly appreciate your comments and discussion on a provocative statement, that women's depression in later life is largely caused by estrogen deficiency at menopause. This statement is made in this new book, and if correct, this may suggest a simple approach to depression treatment:

The Estrogen-Depression Connection: The Hidden Link Between Hormones & Women's Depression
by Karen J., Ph.D. Miller and Steven A., Ph.D. Rogers (Paperback - May 2007)

From book description:

"Research has shown a strong connection between estrogen levels and depression throughout a woman's lifetime. We now understand that abrupt hormonal changes can take a toll on women's moods and even cause serious depression. But the good news is that there is a lot women can do to moderate the effect of these changes."

Please post your comments below!:

Sunday, June 3, 2007

Nutrition and Disease Prevention


A new book has been just published in the "Nutrition and Disease Prevention" book series:

Geriatric Nutrition (Nutrition and Disease Prevention)
by John E. Morley and David R. Thomas

Book Description
Drawing from a group of outstanding experts in the field, Geriatric Nutrition ties basic research with clinical practice in a state-of-the-art review of current nutritional thinking. Beginning with an overview on nutrition in older persons, the book addresses nutritional requirements, techniques for the clinical assessment of nutrition in older adults, and the management of undernutrition in nursing homes and assisted living environments. A significant portion of the book covers nutrition recommendations in specific disease states, such as psychological issues, obesity, diabetes, cancer, anemia, and fracture risk. The book also considers multicultural and ethical issues relevant to the sensitive treatment of older individuals.

Key words:
New books, Nutrition, Disease Prevention, Geriatric Nutrition, John E. Morley, David R. Thomas, Health, fitness, health-care for seniors, life-extension, aging, ageing, longevity, gerontology, gerontological, geriatrics, geriatric, senescence, obesity, diabetes, cancer, anemia, fracture risk

Hope it helps,

Kind regards,

-- Leonid Gavrilov, Ph.D.
My books:

P.S.: See also the list of 26 new books on aging and longevity, which have become available this month:

Saturday, June 2, 2007

No danger is larger than that related to ageing

"No danger is larger than that related to ageing"

said the Cuban President Fidel Castro:

Have a nice weekend :)